InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acacb

Summary

InnateDB Protein

IDBP-192286.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Acacb

Protein Name

acetyl-Coenzyme A carboxylase beta

Synonyms

Acc2; Accb; AI597064; AW743042;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031583

InnateDB Gene

IDBG-192282 (Acacb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003989	acetyl-CoA carboxylase activity
GO:0004075	biotin carboxylase activity
GO:0005524	ATP binding
GO:0009374	biotin binding
GO:0016874	ligase activity
GO:0046872	metal ion binding

Biological Process

GO:0006084	acetyl-CoA metabolic process
GO:0006633	fatty acid biosynthetic process
GO:0008152	metabolic process
GO:0014070	response to organic cyclic compound
GO:0042493	response to drug
GO:0051289	protein homotetramerization

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:2140940

InterPro

IPR000022 Carboxyl transferase
IPR000089 Biotin/lipoyl attachment
IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
IPR005481 Carbamoyl-phosphate synthase, large subunit, N-terminal
IPR005482 Biotin carboxylase, C-terminal
IPR011053 Single hybrid motif
IPR011054 Rudiment single hybrid motif
IPR011761 ATP-grasp fold
IPR011762 Acetyl-coenzyme A carboxyltransferase, N-terminal
IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal
IPR011764 Biotin carboxylation domain
IPR013537 Acetyl-CoA carboxylase, central domain
IPR016185 Pre-ATP-grasp domain
IPR029045 ClpP/crotonase-like domain

PFAM

PF01039
PF00364
PF02786
PF00289
PF02785
PF08326

PRINTS

PIRSF

SMART

SM00878

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite