Version 5.4
Mus musculus Protein: Cog4
Summary
InnateDB Protein IDBP-192344.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cog4
Protein Name component of oligomeric golgi complex 4
Synonyms AW554810; D8Ertd515e;
Species Mus musculus
Ensembl Protein ENSMUSP00000034203
InnateDB Gene IDBG-192342 (Cog4)
Protein Structure
UniProt Annotation
Function Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0007030 Golgi organization
GO:0015031 protein transport
GO:0048213 Golgi vesicle prefusion complex stabilization
Cellular Component
GO:0000139 Golgi membrane
GO:0017119 Golgi transport complex
Protein Structure and Domains
PDB ID MGI:2142808
InterPro IPR013167 Conserved oligomeric Golgi complex, subunit 4
PFAM PF08318
PRINTS
PIRSF
SMART SM00762
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1U1
PhosphoSite PhosphoSite-Q8R1U1
TrEMBL Q7TSQ9
UniProt Splice Variant
Entrez Gene 102339
UniGene Mm.272930
RefSeq NP_598734
MGI ID
MGI Symbol Cog4
OMIM
CCDS CCDS40477
HPRD
IMGT
EMBL AC132945 AK172465 AY223866 BC023120 CH466525
GenPept AAH23120 AAP20648 BAE43019 EDL11474

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca