InnateDB Protein
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IDBP-192588.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Faim
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Protein Name
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Fas apoptotic inhibitory molecule
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000035038
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InnateDB Gene
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IDBG-192586 (Faim)
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Protein Structure
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Function |
Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. {ECO:0000269PubMed:10075978}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:19168072}.
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Disease Associations |
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Tissue Specificity |
Widely expressed, with the highest levels in brain, thymus, kidney, and spleen. {ECO:0000269PubMed:10075978}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
GO:0006915
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apoptotic process
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GO:0043066
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negative regulation of apoptotic process
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GO:1902042
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negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
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Cellular Component |
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PDB ID |
MGI:1344387
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InterPro |
IPR010695
Fas apoptotic inhibitory molecule
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PFAM |
PF06905
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9WUD8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23873
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UniGene |
|
RefSeq |
NP_035940
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MGI ID |
2KD2
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MGI Symbol |
Faim
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OMIM |
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CCDS |
CCDS23431
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HPRD |
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IMGT |
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EMBL |
AF130367
AK005762
BC079662
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GenPept |
AAD23879
AAH79662
BAB24225
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