Version 5.4
Mus musculus Protein: Cep70
Summary
InnateDB Protein IDBP-192727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep70
Protein Name centrosomal protein 70
Synonyms 6720484E09Rik; Bite; C030018L16Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000091312
InnateDB Gene IDBG-192723 (Cep70)
Protein Structure
UniProt Annotation
Function Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1915371
InterPro IPR019734 Tetratricopeptide repeat
PFAM PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6IQY5
PhosphoSite PhosphoSite-Q6IQY5
TrEMBL
UniProt Splice Variant
Entrez Gene 68121
UniGene Mm.475559
RefSeq NP_076362
MGI ID
MGI Symbol Cep70
OMIM
CCDS CCDS40738
HPRD
IMGT
EMBL AF242319 AK020174 AK020622 AK133048 BC050819 BC071260
GenPept AAF97768 AAH50819 AAH71260 BAB32020 BAB32153 BAE21486

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca