Version 5.4
Mus musculus Protein: Tbc1d30
Summary
InnateDB Protein IDBP-192791.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d30
Protein Name TBC1 domain family, member 30
Synonyms 4930505D03Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000070488
InnateDB Gene IDBG-192789 (Tbc1d30)
Protein Structure
UniProt Annotation
Function GTPase-activating protein (GAP) with broad specificity. Acts as a GAP for RAB3A. Also exhibits significant GAP activity toward RAB22A, RAB27A, and RAB35 in vitro (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1921944
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q69ZT9
PhosphoSite PhosphoSite-AAH59081
TrEMBL
UniProt Splice Variant
Entrez Gene 74694
UniGene Mm.472937
RefSeq NP_083333
MGI ID
MGI Symbol Tbc1d30
OMIM
CCDS CCDS48704
HPRD
IMGT
EMBL AK044521 AK173079 BC059081 BC079587 BC138285 BC138286
GenPept AAH59081 AAH79587 AAI38286 AAI38287 BAC31963 BAD32357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca