Version 5.4
Mus musculus Protein: Gns
Summary
InnateDB Protein IDBP-192816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gns
Protein Name glucosamine (N-acetyl)-6-sulfatase
Synonyms 2610016K11Rik; AU042285; C87209; G6S; N28088;
Species Mus musculus
Ensembl Protein ENSMUSP00000043167
InnateDB Gene IDBG-192814 (Gns)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008449 N-acetylglucosamine-6-sulfatase activity
GO:0008484 sulfuric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
GO:0030203 glycosaminoglycan metabolic process
Cellular Component
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1922862
InterPro IPR000917 Sulfatase
IPR012251 N-acetylglucosamine-6-sulfatase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF00884
PRINTS
PIRSF PIRSF036666
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BFR4
PhosphoSite PhosphoSite-
TrEMBL Q6PCZ1
UniProt Splice Variant
Entrez Gene 75612
UniGene Mm.391753
RefSeq NP_083640
MGI ID
MGI Symbol Gns
OMIM
CCDS CCDS24210
HPRD
IMGT
EMBL AK030773 AK049162 AK054046 AK083597 AK149863 AK151037 AK159562 AK165180 AK169485 AK170791 BC055328 BC059047
GenPept AAH55328 AAH59047 BAC27129 BAC33578 BAC35632 BAC38966 BAE29132 BAE30054 BAE35186 BAE38063 BAE41197 BAE42031

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca