Version 5.4
| Mus musculus Protein: Pdpr | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-192909.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Pdpr | ||||||||
| Protein Name | pyruvate dehydrogenase phosphatase regulatory subunit | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000046639 | ||||||||
| InnateDB Gene | IDBG-192907 (Pdpr) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine. {ECO:0000250}. | ||||||||
| Subcellular Localization | Mitochondrion matrix {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2442188 | ||||||||
| InterPro |
IPR003953
FAD binding domain IPR006076 FAD dependent oxidoreductase IPR006222 Glycine cleavage T-protein, N-terminal IPR013977 Glycine cleavage T-protein, C-terminal barrel domain IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain |
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| PFAM |
PF00890
PF01266 PF01571 PF08669 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q7TSQ8 | ||||||||
| PhosphoSite | PhosphoSite-Q7TSQ8 | ||||||||
| TrEMBL | D3Z443 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 319518 | ||||||||
| UniGene | Mm.370024 | ||||||||
| RefSeq | NP_938050 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Pdpr | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22670 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC093451 AK129472 AY223867 BC120745 BC125425 | ||||||||
| GenPept | AAI20746 AAI25426 AAP20649 BAC98282 | ||||||||