Version 5.4
Mus musculus Protein: Wdr59
Summary
InnateDB Protein IDBP-193273.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr59
Protein Name WD repeat domain 59
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000043671
InnateDB Gene IDBG-193271 (Wdr59)
Protein Structure
UniProt Annotation
Function As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2442115
InterPro IPR001680 WD40 repeat
IPR006575 RWD domain
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PF05773
PRINTS
PIRSF
SMART SM00320
SM00591
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C0M0
PhosphoSite PhosphoSite-Q8C0M0
TrEMBL
UniProt Splice Variant
Entrez Gene 319481
UniGene Mm.247294
RefSeq NP_001164214
MGI ID
MGI Symbol Wdr59
OMIM
CCDS CCDS52672
HPRD
IMGT
EMBL AK030644 AK040807 AK052262 AK136303 AK170910 AK173301 BC066082 EF011622
GenPept AAH66082 ABK41112 BAC27062 BAC30708 BAC34902 BAD32579 BAE22922 BAE42108

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca