Version 5.4
Mus musculus Protein: Fmod
Summary
InnateDB Protein IDBP-193293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fmod
Protein Name fibromodulin
Synonyms AI131919; AU041740; SLRR2E;
Species Mus musculus
Ensembl Protein ENSMUSP00000035489
InnateDB Gene IDBG-193291 (Fmod)
Protein Structure
UniProt Annotation
Function Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity Highest levels observed in knee epiphysis, in calvarial and diaphyseal bone, in nasal and costal cartilage, in the eye, and in bladder. In mature knee joint it is mostly present in the proliferating zone of growth plate. It is also observed in ligaments, especially at insertion sites, in the junction between meniscus and joint capsule, in the perimysium of skeletal muscle and in the periosteum.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID MGI:1328364
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50608
PhosphoSite PhosphoSite-P50608
TrEMBL Q543D2
UniProt Splice Variant
Entrez Gene 14264
UniGene Mm.418270
RefSeq NP_067330
MGI ID
MGI Symbol Fmod
OMIM
CCDS CCDS15301
HPRD
IMGT
EMBL AC154872 AK032302 AK053317 AK054183 AK082593 BC064779 CH466520 X94998
GenPept AAH64779 BAC27801 BAC35342 BAC35685 BAC38543 CAA64454 EDL39631

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca