InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Acads

Summary

InnateDB Protein

IDBP-193313.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acads

Protein Name

acyl-Coenzyme A dehydrogenase, short chain

Synonyms

AI196007; Bcd-1; Bcd1; Hdlq8; SCAD;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031524

InnateDB Gene

IDBG-193311 (Acads)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000062	fatty-acyl-CoA binding
GO:0003995	acyl-CoA dehydrogenase activity
GO:0004085	butyryl-CoA dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0008152	metabolic process
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042594	response to starvation
GO:0046359	butyrate catabolic process
GO:0051289	protein homotetramerization
GO:0051384	response to glucocorticoid
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:87868

InterPro

IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
IPR013107 Acyl-CoA dehydrogenase, type 2, C-terminal
IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal

PFAM

PF02770
PF00441
PF08028
PF02771

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q07417

PhosphoSite