InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MOB2

Summary

InnateDB Protein

IDBP-19341.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MOB2

Protein Name

MOB kinase activator 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000328694

InnateDB Gene

IDBG-19339 (MOB2)

Protein Structure

UniProt Annotation

Function

Stimulates the autophosphorylation and kinase activity of STK38 and STK38L. {ECO:0000269PubMed:15067004}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:15067004}. Cytoplasm, perinuclear region {ECO:0000269PubMed:15067004}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0046872	metal ion binding

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0010976	positive regulation of neuron projection development
GO:0030036	actin cytoskeleton organization

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0044306	neuron projection terminus
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR005301 Mob1/phocein

PFAM

PF03637

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q70IA6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

81532

UniGene

Hs.370360

RefSeq

NP_001165694

HUGO

HGNC:24904

OMIM

611969

CCDS

CCDS53591

HPRD

17581

IMGT

EMBL

AC091196 AJ580639 AK057350 AK296658 BC047291 BC067785

GenPept

AAH47291 AAH67785 BAB71443 BAG59255 CAE45271