InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd44

Summary

InnateDB Protein

IDBP-193507.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd44

Protein Name

CD44 antigen

Synonyms

AU023126; AW121933; AW146109; HERMES; Ly-24; Pgp-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000005218

InnateDB Gene

IDBG-193505 (Cd44)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004415	hyalurononglucosaminidase activity
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0005540	hyaluronic acid binding

Biological Process

GO:0001658	branching involved in ureteric bud morphogenesis
GO:0002246	wound healing involved in inflammatory response
GO:0007155	cell adhesion
GO:0010628	positive regulation of gene expression
GO:0016055	Wnt signaling pathway
GO:0030214	hyaluronan catabolic process
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0034116	positive regulation of heterotypic cell-cell adhesion
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044344	cellular response to fibroblast growth factor stimulus
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0051216	cartilage development
GO:0060442	branching involved in prostate gland morphogenesis
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0070487	monocyte aggregation
GO:1900625	positive regulation of monocyte aggregation
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016323	basolateral plasma membrane
GO:0070062	extracellular vesicular exosome