InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pccb

Summary

InnateDB Protein

IDBP-193544.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pccb

Protein Name

propionyl Coenzyme A carboxylase, beta polypeptide

Synonyms

1300012P06Rik; AI314687; R74805;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035116

InnateDB Gene

IDBG-193542 (Pccb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Broadly expressed. Most abundantly expressed in the kidney, liver, small intestine and stomach. {ECO:0000269PubMed:11245989}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004658	propionyl-CoA carboxylase activity
GO:0005524	ATP binding
GO:0016874	ligase activity

Biological Process

GO:0008152

metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:1914154

InterPro

IPR000022 Carboxyl transferase
IPR011762 Acetyl-coenzyme A carboxyltransferase, N-terminal
IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal
IPR029045 ClpP/crotonase-like domain

PFAM

PF01039

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99MN9

PhosphoSite