Version 5.4
| Mus musculus Protein: Dennd1c | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-193585.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Dennd1c | ||||||
| Protein Name | DENN/MADD domain containing 1C | ||||||
| Synonyms | 4432409M07Rik; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000011623 | ||||||
| InnateDB Gene | IDBG-193583 (Dennd1c) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:1918035 | ||||||
| InterPro |
IPR001194
DENN domain IPR005112 dDENN domain IPR005113 uDENN domain |
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| PFAM |
PF02141
PF03455 PF03456 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00799
SM00801 SM00800 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q8CFK6 | ||||||
| PhosphoSite | PhosphoSite-Q8CFK6 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 70785 | ||||||
| UniGene | Mm.481264 | ||||||
| RefSeq | NP_705779 | ||||||
| MGI ID | |||||||
| MGI Symbol | Dennd1c | ||||||
| OMIM | |||||||
| CCDS | CCDS37669 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK014482 BC035208 | ||||||
| GenPept | AAH35208 BAB29384 | ||||||