Version 5.4
Mus musculus Protein: RNASEK
Summary
InnateDB Protein IDBP-193996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNASEK
Protein Name ribonuclease, RNase K
Synonyms 2310033H11Rik; AA571397; D11Bwg0434e;
Species Mus musculus
Ensembl Protein ENSMUSP00000048271
InnateDB Gene IDBG-709415 (RNASEK)
Protein Structure
UniProt Annotation
Function Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004521 endoribonuclease activity
Biological Process
GO:0009303 rRNA transcription
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:106369
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K3C0
PhosphoSite PhosphoSite-
TrEMBL H3BJV0
UniProt Splice Variant
Entrez Gene 52898
UniGene
RefSeq NP_776103
MGI ID
MGI Symbol Rnasek
OMIM
CCDS CCDS36204
HPRD
IMGT
EMBL AK009592 AK171975 AL669869 BC021602 BC021603 BC024417 CH466596 CR933731
GenPept AAH21602 AAH21603 AAH24417 BAC25261 BAE42755 CAI35234 CAM28103 EDL12546 EDL12547 EDL12549

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca