Version 5.4
| Mus musculus Protein: Slco2a1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-194148.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Slco2a1 | ||||||||
| Protein Name | solute carrier organic anion transporter family, member 2a1 | ||||||||
| Synonyms | 2310021C19Rik; mPgt; Pgt; Slc21a2; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000035148 | ||||||||
| InnateDB Gene | IDBG-194146 (Slco2a1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A. | ||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Highly expressed in lung and liver. Detected at lower levels in kidney and skeletal muscle. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1346021 | ||||||||
| InterPro |
IPR002350
Kazal domain IPR004156 Organic anion transporter polypeptide OATP IPR011701 Major facilitator superfamily IPR016196 Major facilitator superfamily domain, general substrate transporter IPR020846 Major facilitator superfamily domain |
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| PFAM |
PF00050
PF07648 PF03137 PF07690 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00280
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9EPT5 | ||||||||
| PhosphoSite | PhosphoSite-Q9EPT5 | ||||||||
| TrEMBL | Q3TED0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 24059 | ||||||||
| UniGene | Mm.405285 | ||||||||
| RefSeq | NP_201571 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Slco2a1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS23448 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF323958 AK166724 AK169706 BC035200 CH466560 | ||||||||
| GenPept | AAG40332 AAH35200 BAE38971 BAE41318 EDL21061 EDL21063 | ||||||||