Version 5.4
Mus musculus Protein: Pex11a
Summary
InnateDB Protein IDBP-194269.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pex11a
Protein Name peroxisomal biogenesis factor 11 alpha
Synonyms PEX11alpha;
Species Mus musculus
Ensembl Protein ENSMUSP00000032761
InnateDB Gene IDBG-194265 (Pex11a)
Protein Structure
UniProt Annotation
Function May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity). {ECO:0000250}.
Subcellular Localization Peroxisome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Strongly expressed in liver and at lower levels in heart, brain, kidney and testis. {ECO:0000269PubMed:12417726}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007031 peroxisome organization
GO:0007165 signal transduction
GO:0016557 peroxisome membrane biogenesis
GO:0016559 peroxisome fission
GO:0044375 regulation of peroxisome size
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1338788
InterPro IPR008733 Peroxisomal biogenesis factor 11
PFAM PF05648
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z211
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 18631
UniGene Mm.399947
RefSeq NP_035198
MGI ID
MGI Symbol Pex11a
OMIM
CCDS CCDS21386
HPRD
IMGT
EMBL AF093669 AK078954 BC023439
GenPept AAC78659 AAH23439 BAC37477

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca