Version 5.4
Mus musculus Protein: 1300017J02Rik
Summary
InnateDB Protein IDBP-194317.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 1300017J02Rik
Protein Name RIKEN cDNA 1300017J02 gene
Synonyms Ica; mICA;
Species Mus musculus
Ensembl Protein ENSMUSP00000035163
InnateDB Gene IDBG-194315 (1300017J02Rik)
Protein Structure
UniProt Annotation
Function Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions. {ECO:0000269PubMed:17511619, ECO:0000269PubMed:18712936}.
Subcellular Localization Secreted {ECO:0000269PubMed:17511619}.
Disease Associations
Tissue Specificity Detected in blood plasma, heart, kidney, liver, colon, lung, spleen, pancreas and testis (at protein level). {ECO:0000269PubMed:17511619}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004857 enzyme inhibitor activity
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 cellular iron ion homeostasis
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1919025
InterPro IPR001156 Transferrin family
IPR016357 Transferrin
PFAM PF00405
PRINTS PR00422
PIRSF PIRSF002549
SMART SM00094
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DBD0
PhosphoSite PhosphoSite-Q9DBD0
TrEMBL
UniProt Splice Variant
Entrez Gene 71775
UniGene Mm.18802
RefSeq NP_082194
MGI ID 3MC2
MGI Symbol 1300017J02Rik
OMIM
CCDS CCDS23452
HPRD
IMGT
EMBL AC122747 AK005035
GenPept BAB23762

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca