Version 5.4
Mus musculus Protein: Sema4b
Summary
InnateDB Protein IDBP-194651.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sema4b
Protein Name sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms mKIAA1745; Semac; SemC;
Species Mus musculus
Ensembl Protein ENSMUSP00000032754
InnateDB Gene IDBG-194649 (Sema4b)
Protein Structure
UniProt Annotation
Function Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:107559
InterPro IPR001627 Sema domain
IPR002165 Plexin
IPR016201 Plexin-like fold
PFAM PF01403
PF01437
PRINTS
PIRSF
SMART SM00630
SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62179
PhosphoSite PhosphoSite-Q62179
TrEMBL F2Z3W4
UniProt Splice Variant
Entrez Gene 20352
UniGene Mm.427382
RefSeq NP_038687
MGI ID
MGI Symbol Sema4b
OMIM
CCDS CCDS21391
HPRD
IMGT
EMBL AC109232 AK173249 DQ073331 X85992
GenPept AAY82464 BAD32527 CAA59984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca