InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mars

Summary

InnateDB Protein

IDBP-194894.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mars

Protein Name

methionine-tRNA synthetase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037446

InnateDB Gene

IDBG-194892 (Mars)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	42 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004825	methionine-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006431	methionyl-tRNA aminoacylation

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1345633

InterPro

IPR000738 WHEP-TRS
IPR009068 S15/NS1, RNA-binding
IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold
IPR014758 Methionyl-tRNA synthetase
IPR015413 Methionyl/Leucyl tRNA synthetase
IPR029038 Methionyl-tRNA synthetase, Zn-domain

PFAM

PF00458
PF13098
PF13192
PF13462
PF13905
PF09334

PRINTS

PR01041

PIRSF

SMART

SM00991

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt