InnateDB Protein
|
IDBP-19492.5
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
TAS2R9
|
Protein Name
|
taste receptor, type 2, member 9
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000240691
|
InnateDB Gene
|
IDBG-19490 (TAS2R9)
|
Protein Structure
|
|
Function |
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Membrane; Multi-pass membrane protein.
|
Disease Associations |
|
Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
|
Biological Process |
GO:0007186
|
G-protein coupled receptor signaling pathway
|
GO:0008150
|
biological_process
|
GO:0050909
|
sensory perception of taste
|
GO:0050912
|
detection of chemical stimulus involved in sensory perception of taste
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR007960
Mammalian taste receptor
IPR017452
GPCR, rhodopsin-like, 7TM
|
PFAM |
PF05296
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9NYW1
|
PhosphoSite |
PhosphoSite-Q9NYW1
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
50835
|
UniGene |
Hs.272391
|
RefSeq |
NP_076406
|
HUGO |
HGNC:14917
|
OMIM |
604795
|
CCDS |
CCDS8633
|
HPRD |
07266
|
IMGT |
|
EMBL |
AB199063
AB199064
AB199065
AF227135
AY724954
BC069066
BC095519
|
GenPept |
AAF43908
AAH69066
AAH95519
AAU21150
BAD97966
BAD97967
BAD97968
|
|
|