InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gp1ba

Summary

InnateDB Protein

IDBP-195007.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gp1ba

Protein Name

glycoprotein 1b, alpha polypeptide

Synonyms

GPIba; GPIbalpha;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057563

InnateDB Gene

IDBG-195005 (Gp1ba)

Protein Structure

UniProt Annotation

Function

GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. {ECO:0000250}.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000902	cell morphogenesis
GO:0007155	cell adhesion
GO:0007596	blood coagulation
GO:0007599	hemostasis
GO:0042730	fibrinolysis

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0031362	anchored component of external side of plasma membrane