Version 5.4
Mus musculus Protein: Rnf167
Summary
InnateDB Protein IDBP-195063.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf167
Protein Name ring finger protein 167
Synonyms 0610010G05Rik; 5730408C10Rik; AU019305; AV328608;
Species Mus musculus
Ensembl Protein ENSMUSP00000036472
InnateDB Gene IDBG-195059 (Rnf167)
Protein Structure
UniProt Annotation
Function May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition (By similarity). {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000250}; Single- pass membrane protein {ECO:0000250}. Note=Targeted to cytoplasmic membranes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0045786 negative regulation of cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1917760
InterPro IPR001841 Zinc finger, RING-type
IPR003137 Protease-associated domain, PA
IPR011016 Zinc finger, RING-CH-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF02225
PF12906
PF00097
PRINTS
PIRSF
SMART SM00184
SM00744
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91XF4
PhosphoSite PhosphoSite-Q91XF4
TrEMBL
UniProt Splice Variant
Entrez Gene 70510
UniGene Mm.488722
RefSeq NP_081721
MGI ID
MGI Symbol Rnf167
OMIM
CCDS CCDS24959
HPRD
IMGT
EMBL AK154071 AL596117 BC010777
GenPept AAH10777 BAE32356 CAI25167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca