Version 5.4
| Mus musculus Protein: Inhbe | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-195087.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Inhbe | ||||||
| Protein Name | inhibin beta E | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000053977 | ||||||
| InnateDB Gene | IDBG-195085 (Inhbe) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | ||||||
| Subcellular Localization | Secreted {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:109269 | ||||||
| InterPro |
IPR001318
Inhibin, beta C subunit IPR001839 Transforming growth factor-beta, C-terminal IPR029034 Cystine-knot cytokine |
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| PFAM |
PF00019
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| PRINTS |
PR00672
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| PIRSF | |||||||
| SMART |
SM00204
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | O08717 | ||||||
| PhosphoSite | PhosphoSite-O08717 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 16326 | ||||||
| UniGene | Mm.3510 | ||||||
| RefSeq | NP_032408 | ||||||
| MGI ID | |||||||
| MGI Symbol | Inhbe | ||||||
| OMIM | |||||||
| CCDS | CCDS24239 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | BC010404 CH466578 U96386 | ||||||
| GenPept | AAB53801 AAH10404 EDL24502 | ||||||