InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Immp1l

Summary

InnateDB Protein

IDBP-195230.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Immp1l

Protein Name

IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Synonyms

1500034J20Rik; 2610528O17Rik; AU042386;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000049044

InnateDB Gene

IDBG-195228 (Immp1l)

Protein Structure

UniProt Annotation

Function

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008236	serine-type peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0006627	protein processing involved in protein targeting to mitochondrion
GO:0008150	biological_process

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0042720	mitochondrial inner membrane peptidase complex

Protein Structure and Domains

PDB ID

MGI:1913791

InterPro

IPR000223 Peptidase S26A, signal peptidase I
IPR015927 Peptidase S24/S26A/S26B/S26C
IPR019533 Peptidase S26
IPR019759 Peptidase S24/S26A/S26B

PFAM

PF10502
PF00717

PRINTS

PR00727

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CQU8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

66541

UniGene

RefSeq

NP_082536

MGI ID

MGI Symbol

Immp1l

OMIM

CCDS

CCDS38192

HPRD

IMGT

EMBL

AK005356 AK009570 AK010075 AK011278 AK011382 AK011420 AK011466 AK011618 AK011872 AK012181 AK015978 AK078300 AK135670 AK168202 BC008259 BC081433

GenPept

AAH08259 AAH81433 BAB23971 BAB26367 BAB26684 BAB27512 BAB27582 BAB27608 BAB27637 BAB27737 BAB27891 BAB28082 BAB30062 BAC37210 BAE22608 BAE40162