InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hsbp1

Summary

InnateDB Protein

IDBP-195309.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hsbp1

Protein Name

heat shock factor binding protein 1

Synonyms

0610007A03Rik; AA408769; Hsp25;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034300

InnateDB Gene

IDBG-195307 (Hsbp1)

Protein Structure

UniProt Annotation

Function

Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006936

muscle contraction

Cellular Component

GO:0005634	nucleus
GO:0005856	cytoskeleton

Protein Structure and Domains

PDB ID

MGI:1915446

InterPro

IPR009643 Heat shock factor binding 1

PFAM

PF06825

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CQZ1

PhosphoSite

PhosphoSite-Q9CQZ1

TrEMBL

UniProt Splice Variant

Entrez Gene

68196

UniGene

Mm.471110

RefSeq

NP_077181

MGI ID

MGI Symbol

Hsbp1

OMIM

CCDS

CCDS40492

HPRD

IMGT

EMBL

AK010939 AK018708 AK050550 AK078498 AK145940 BC002153

GenPept

AAH02153 BAB27281 BAB31359 BAC34319 BAC37310 BAE26770