Version 5.4
Mus musculus Protein: Pigv
Summary
InnateDB Protein IDBP-195329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigv
Protein Name phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000065601
InnateDB Gene IDBG-195325 (Pigv)
Protein Structure
UniProt Annotation
Function Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0097502 mannosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2442480
InterPro IPR007315 GPI mannosyltransferase 2
PFAM PF04188
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TPN3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 230801
UniGene Mm.404033
RefSeq NP_001139428
MGI ID
MGI Symbol Pigv
OMIM
CCDS CCDS51322
HPRD
IMGT
EMBL AK046527 AK047322 AK052446 AK080590 AK080858 AK148285 BC055060
GenPept AAH55060 BAC32773 BAC33023 BAC34995 BAC37950 BAC38047 BAE28458

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca