InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kif1c

Summary

InnateDB Protein

IDBP-195439.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kif1c

Protein Name

kinesin family member 1C

Synonyms

B430105J22Rik; D11Bwg1349e; Ltxs1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000092075

InnateDB Gene

IDBG-195435 (Kif1c)

Protein Structure

UniProt Annotation

Function

Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end- directed motility (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0007018	microtubule-based movement
GO:0008152	metabolic process

Cellular Component

GO:0005794	Golgi apparatus
GO:0005871	kinesin complex
GO:0005874	microtubule

Protein Structure and Domains

PDB ID

MGI:1098260

InterPro

IPR000253 Forkhead-associated (FHA) domain
IPR001752 Kinesin, motor domain
IPR008984 SMAD/FHA domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00498
PF00225

PRINTS

PR00380

PIRSF

SMART

SM00240
SM00129

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt