InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP210

Summary

InnateDB Protein

IDBP-19568.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP210

Protein Name

nucleoporin 210kDa

Synonyms

GP210; POM210;

Species

Homo sapiens

Ensembl Protein

ENSP00000254508

InnateDB Gene

IDBG-19566 (NUP210)

Protein Structure

UniProt Annotation

Function

Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. {ECO:0000269PubMed:14517331}.

Subcellular Localization

Nucleus, nuclear pore complex {ECO:0000269PubMed:2195063}. Nucleus membrane {ECO:0000269PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269PubMed:2195063}. Endoplasmic reticulum membrane {ECO:0000269PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269PubMed:2195063}.

Disease Associations

Tissue Specificity

Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. {ECO:0000269PubMed:10048485}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0046983	protein dimerization activity

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0055085	transmembrane transport