InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lama1

Summary

InnateDB Protein

IDBP-195775.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lama1

Protein Name

laminin, alpha 1

Synonyms

AA408497; Lama;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000043957

InnateDB Gene

IDBG-195773 (Lama1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	16 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005201	extracellular matrix structural constituent
GO:0005515	protein binding
GO:0043208	glycosphingolipid binding

Biological Process

GO:0002011	morphogenesis of an epithelial sheet
GO:0007155	cell adhesion
GO:0007166	cell surface receptor signaling pathway
GO:0009888	tissue development
GO:0030155	regulation of cell adhesion
GO:0030334	regulation of cell migration
GO:0031175	neuron projection development
GO:0045198	establishment of epithelial cell apical/basal polarity
GO:0045995	regulation of embryonic development
GO:0060041	retina development in camera-type eye
GO:0060441	epithelial tube branching involved in lung morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0061304	retinal blood vessel morphogenesis

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005604	basement membrane
GO:0005605	basal lamina
GO:0005606	laminin-1 complex
GO:0005608	laminin-3 complex
GO:0005615	extracellular space
GO:0005911	cell-cell junction
GO:0031012	extracellular matrix
GO:0043256	laminin complex

Protein Structure and Domains

PDB ID

MGI:99892

InterPro

IPR000034 Laminin B type IV
IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR002049 EGF-like, laminin
IPR008211 Laminin, N-terminal
IPR008979 Galactose-binding domain-like
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR009254 Laminin I
IPR010307 Laminin II
IPR018031 Laminin B, subgroup

PFAM