InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sh3bgrl3

Summary

InnateDB Protein

IDBP-195833.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sh3bgrl3

Protein Name

SH3 domain binding glutamic acid-rich protein-like 3

Synonyms

1110004L05Rik; AU022188;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030651

InnateDB Gene

IDBG-195831 (Sh3bgrl3)

Protein Structure

UniProt Annotation

Function

Could act as a modulator of glutaredoxin biological activity. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005100	Rho GTPase activator activity
GO:0009055	electron carrier activity
GO:0015035	protein disulfide oxidoreductase activity
GO:0030215	semaphorin receptor binding

Biological Process

GO:0008150	biological_process
GO:0030834	regulation of actin filament depolymerization
GO:0032321	positive regulation of Rho GTPase activity
GO:0032956	regulation of actin cytoskeleton organization
GO:0043535	regulation of blood vessel endothelial cell migration
GO:0045454	cell redox homeostasis
GO:0055114	oxidation-reduction process