Version 5.4
| Mus musculus Protein: Poc1a | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-195867.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Poc1a | ||||||||
| Protein Name | POC1 centriolar protein homolog A (Chlamydomonas) | ||||||||
| Synonyms | 2510040D07Rik; Wdr51a; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000072064 | ||||||||
| InnateDB Gene | IDBG-195863 (Poc1a) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Component of both mother and daughter centrioles. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Widely expressed in embryonic and adult tissues. {ECO:0000269PubMed:22840364}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1917485 | ||||||||
| InterPro |
IPR001680
WD40 repeat IPR013979 Translation initiation factor, beta propellor-like domain IPR017986 WD40-repeat-containing domain IPR020472 G-protein beta WD-40 repeat |
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| PFAM |
PF00400
PF08662 |
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| PRINTS |
PR00320
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| PIRSF | |||||||||
| SMART |
SM00320
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8JZX3 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 70235 | ||||||||
| UniGene | Mm.23054 | ||||||||
| RefSeq | NP_081630 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Poc1a | ||||||||
| OMIM | |||||||||
| CCDS | CCDS23474 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK011064 AK154163 BC034901 | ||||||||
| GenPept | AAH34901 BAB27371 BAE32416 | ||||||||