Version 5.4
Mus musculus Protein: Tac2
Summary
InnateDB Protein IDBP-195881.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tac2
Protein Name tachykinin 2
Synonyms Tac3;
Species Mus musculus
Ensembl Protein ENSMUSP00000026466
InnateDB Gene IDBG-195879 (Tac2)
Protein Structure
UniProt Annotation
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007217 tachykinin receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:98476
InterPro IPR003635 Neurokinin-B/Tachykinin-3
PFAM PF03823
PRINTS PR01828
PIRSF PIRSF001843
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55099
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 21334
UniGene Mm.2374
RefSeq NP_033338
MGI ID
MGI Symbol Tac2
OMIM
CCDS CCDS24248
HPRD
IMGT
EMBL AF186116 BC051476 D14423
GenPept AAF01434 AAH51476 BAA03316

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca