Version 5.4
Mus musculus Protein: Ddit4l
Summary
InnateDB Protein IDBP-195954.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddit4l
Protein Name DNA-damage-inducible transcript 4-like
Synonyms 1700037B15Rik; 1700108M02Rik; REDD2; RTP801L; Smhs1;
Species Mus musculus
Ensembl Protein ENSMUSP00000058896
InnateDB Gene IDBG-195952 (Ddit4l)
Protein Structure
UniProt Annotation
Function Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0009968 negative regulation of signal transduction
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1920534
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR012918 RTP801-like
PFAM PF07809
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VHZ5
PhosphoSite PhosphoSite-Q8VHZ5
TrEMBL E9Q253
UniProt Splice Variant
Entrez Gene 73284
UniGene Mm.396051
RefSeq NP_084419
MGI ID
MGI Symbol Ddit4l
OMIM
CCDS CCDS17863
HPRD
IMGT
EMBL AC140486 AF327512 AF335325 AK006617 AK018944 AK029362 AK053333 BC038131 BC147181 BC147182 CH466532
GenPept AAH38131 AAI47182 AAI47183 AAL38425 AAL39013 BAB24676 BAB31490 BAC26417 BAC35350 EDL12121

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca