Version 5.4
| Mus musculus Protein: Dennd1b | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-196181.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Dennd1b | ||||||
| Protein Name | DENN/MADD domain containing 1B | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000092082 | ||||||
| InnateDB Gene | IDBG-196179 (Dennd1b) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Guanine nucleotide exchange factor (GEF) for RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. May play a role in clathrin- mediated endocytosis. | ||||||
| Subcellular Localization | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:2447812 | ||||||
| InterPro |
IPR001194
DENN domain IPR005112 dDENN domain |
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| PFAM |
PF02141
PF03455 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00799
SM00801 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q3U1T9 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 329260 | ||||||
| UniGene | Mm.474921 | ||||||
| RefSeq | NP_851992 | ||||||
| MGI ID | |||||||
| MGI Symbol | Dennd1b | ||||||
| OMIM | |||||||
| CCDS | CCDS35728 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AC117623 AC138741 AK015524 AK155727 BC042698 BC141388 BC141389 | ||||||
| GenPept | AAH42698 AAI41389 AAI41390 BAB29881 BAE33404 | ||||||