Version 5.4
Mus musculus Protein: Parp3
Summary
InnateDB Protein IDBP-196247.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Parp3
Protein Name poly (ADP-ribose) polymerase family, member 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000064513
InnateDB Gene IDBG-196245 (Parp3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006302 double-strand break repair
GO:0006471 protein ADP-ribosylation
GO:0051106 positive regulation of DNA ligation
GO:0060236 regulation of mitotic spindle organization
GO:1990166 protein localization to site of double-strand break
Cellular Component
GO:0035861 site of double-strand break
Protein Structure and Domains
PDB ID MGI:1891258
InterPro IPR004102 Poly(ADP-ribose) polymerase, regulatory domain
IPR008893 WGR domain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
PFAM PF02877
PF05406
PF00644
PRINTS
PIRSF
SMART SM00773
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8CFB8
UniProt Splice Variant
Entrez Gene 235587
UniGene Mm.273659
RefSeq NP_663594
MGI ID
MGI Symbol Parp3
OMIM
CCDS CCDS23480
HPRD
IMGT
EMBL AC151729 AF368233 AK170541 AY046316 AY046317
GenPept AAL08055 AAL08056 AAN62793 BAE41867

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca