Version 5.4
Mus musculus Protein: Gins2
Summary
InnateDB Protein IDBP-196387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gins2
Protein Name GINS complex subunit 2 (Psf2 homolog)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000034278
InnateDB Gene IDBG-196385 (Gins2)
Protein Structure
UniProt Annotation
Function The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1921019
InterPro IPR016906 GINS complex, subunit Psf2, subgroup
IPR021151 GINS complex
PFAM PF05916
PRINTS
PIRSF PIRSF028998
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D600
PhosphoSite PhosphoSite-Q9D600
TrEMBL
UniProt Splice Variant
Entrez Gene 272551
UniGene Mm.444335
RefSeq NP_849187
MGI ID
MGI Symbol Gins2
OMIM
CCDS CCDS40496
HPRD
IMGT
EMBL AK014776 AK028375 AK030758 BC082565
GenPept AAH82565 BAB29546 BAC25914 BAC27124

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca