Version 5.4
Mus musculus Protein: Btbd1
Summary
InnateDB Protein IDBP-196575.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Btbd1
Protein Name BTB (POZ) domain containing 1
Synonyms 1190005H08Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000026093
InnateDB Gene IDBG-196573 (Btbd1)
Protein Structure
UniProt Annotation
Function Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization Cytoplasm, P-body {ECO:0000250}. Note=Cytoplasmic bodies. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1933765
InterPro IPR000210 BTB/POZ-like
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
IPR012983 PHR
IPR013069 BTB/POZ
PFAM PF07707
PF08005
PF00651
PRINTS
PIRSF
SMART SM00225
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58544
PhosphoSite PhosphoSite-P58544
TrEMBL
UniProt Splice Variant
Entrez Gene 83962
UniGene Mm.483832
RefSeq NP_666305
MGI ID
MGI Symbol Btbd1
OMIM
CCDS CCDS21407
HPRD
IMGT
EMBL AK088345 BC031192 BC072618
GenPept AAH31192 AAH72618 BAC40296

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca