InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: F13b

Summary

InnateDB Protein

IDBP-196632.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

F13b

Protein Name

coagulation factor XIII, beta subunit

Synonyms

Cf-13b; Cf13b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027615

InnateDB Gene

IDBG-196630 (F13b)

Protein Structure

UniProt Annotation

Function

The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Predominantly expressed in liver and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0007596	blood coagulation
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005576	extracellular region

Protein Structure and Domains

PDB ID

MGI:88379

InterPro

IPR000436 Sushi/SCR/CCP

PFAM

PF00084

PRINTS

PIRSF

SMART

SM00032

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q07968

PhosphoSite

PhosphoSite-Q07968

TrEMBL

UniProt Splice Variant

Entrez Gene

14060

UniGene

Mm.400771

RefSeq

NP_112441

MGI ID

MGI Symbol

F13b

OMIM

CCDS

CCDS48386

HPRD

IMGT

EMBL

AC158946 AL837518 CH466520 D10071

GenPept

BAA00963 CAM20501 EDL39526