InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aven

Summary

InnateDB Protein

IDBP-196735.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aven

Protein Name

apoptosis, caspase activation inhibitor

Synonyms

1700013A01Rik; 1700056A21Rik; mAven-L; mAven-S;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003705

InnateDB Gene

IDBG-196731 (Aven)

Protein Structure

UniProt Annotation

Function

Protects against apoptosis mediated by Apaf-1. {ECO:0000250}.

Subcellular Localization

Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with intracellular membranes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006915	apoptotic process
GO:0043066	negative regulation of apoptotic process

Cellular Component

GO:0005622	intracellular
GO:0012505	endomembrane system
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1921518

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D9K3

PhosphoSite

PhosphoSite-Q9D9K3

TrEMBL

UniProt Splice Variant

Entrez Gene

74268

UniGene

Mm.479491

RefSeq

NP_083120

MGI ID

MGI Symbol

Aven

OMIM

CCDS

CCDS16557

HPRD

IMGT

EMBL

AK006808 AL691423 AL731840 CH466519

GenPept

BAB24752 CAM17844 CAM25808 EDL27845