Mus musculus Protein: Rph3a
Summary
InnateDB Protein IDBP-196781.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rph3a
Protein Name rabphilin 3A
Synonyms 2900002P20Rik; AU022689; AW108370;
Species Mus musculus
Ensembl Protein ENSMUSP00000078198
InnateDB Gene IDBG-196779 (Rph3a)
Protein Structure
UniProt Annotation
Function Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Subcellular Localization Cell junction, synapse {ECO:0000250}. Membrane {ECO:0000305PubMed:18945677}; Peripheral membrane protein {ECO:0000305PubMed:18945677}.
Disease Associations
Tissue Specificity Specifically expressed in brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0030054 cell junction
Protein Structure and Domains
PDB ID MGI:102788
InterPro IPR000008 C2 domain
IPR001565 Synaptotagmin
IPR010911 Zinc finger, FYVE-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
PFAM PF00168
PF02318
PRINTS PR00360
PR00399
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47708
PhosphoSite PhosphoSite-P47708
TrEMBL
UniProt Splice Variant
Entrez Gene 19894
UniGene Mm.181166
RefSeq NP_035416
MGI ID 2K3H
MGI Symbol Rph3a
OMIM
CCDS CCDS39246
HPRD
IMGT
EMBL BC042585 BC050883 D29965
GenPept AAH42585 AAH50883 BAA06231