Version 5.4
Mus musculus Protein: Ryr3
Summary
InnateDB Protein IDBP-196812.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Ryr3
Protein Name ryanodine receptor 3
Synonyms AI851294; C230090H21; RYR-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000089426
InnateDB Gene IDBG-196806 (Ryr3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005219 ryanodine-sensitive calcium-release channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0015278 calcium-release channel activity
GO:0048763 calcium-induced calcium release activity
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006941 striated muscle contraction
GO:0051481 negative regulation of cytosolic calcium ion concentration
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030314 junctional membrane complex
GO:0033017 sarcoplasmic reticulum membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:99684
InterPro IPR000699 RIH (RyR and IP3R Homology) domain
IPR001870 B30.2/SPRY domain
IPR002048 EF-hand domain
IPR003032 Ryanodine receptor Ryr
IPR003877 SPla/RYanodine receptor SPRY
IPR005821 Ion transport domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR009460 Ryanodine Receptor TM 4-6
IPR013333 Ryanodine receptor
IPR013662 RyR/IP3R Homology associated domain
IPR014821 Inositol 1,4,5-trisphosphate/ryanodine receptor
IPR016093 MIR motif
IPR018355 SPla/RYanodine receptor subgroup
PFAM PF01365
PF00036
PF13202
PF13405
PF02026
PF00622
PF00520
PF06459
PF08454
PF08709
PF02815
PRINTS PR00795
PIRSF
SMART SM00054
SM00449
SM00472
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-NP_808320
TrEMBL Q4U2G7
UniProt Splice Variant
Entrez Gene 20192
UniGene Mm.436657
RefSeq NP_808320
MGI ID
MGI Symbol Ryr3
OMIM
CCDS CCDS50661
HPRD
IMGT
EMBL AL672250 AL691423 AL732316 AL929348 BX649564 D84236
GenPept BAA12285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca