Version 5.4
Homo sapiens Protein: TAS2R42
Summary
InnateDB Protein IDBP-19689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAS2R42
Protein Name taste receptor, type 2, member 42
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000334050
InnateDB Gene IDBG-19687 (TAS2R42)
Protein Structure
UniProt Annotation
Function Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007960 Mammalian taste receptor
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF05296
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7RTR8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 353164
UniGene Hs.553716
RefSeq NP_852094
HUGO HGNC:18888
OMIM 613966
CCDS CCDS31747
HPRD 18137
IMGT
EMBL AC010176 AY724953 BC131742 BK001099
GenPept AAI31743 AAU21149 DAA01206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca