Version 5.4
Mus musculus Protein: Cyb5d2
Summary
InnateDB Protein IDBP-197155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyb5d2
Protein Name cytochrome b5 domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000078623
InnateDB Gene IDBG-197151 (Cyb5d2)
Protein Structure
UniProt Annotation
Function Heme-binding protein which promotes neuronal but not astrocyte differentiation. {ECO:0000269PubMed:19968755}.
Subcellular Localization Secreted {ECO:0000269PubMed:19968755}.
Disease Associations
Tissue Specificity Expressed in various tissues including brain, heart, adrenal gland, and kidney. In the brain, mainly expressed in pyramidal cells around the CA3 region of Ammon horn in hippocampus. Present in brain (at protein level). {ECO:0000269PubMed:19968755}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0020037 heme binding
Biological Process
GO:0007399 nervous system development
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2684848
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
PFAM PF00173
PRINTS PR00363
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SSH8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 192986
UniGene Mm.488420
RefSeq NP_001020097
MGI ID
MGI Symbol Cyb5d2
OMIM
CCDS CCDS24990
HPRD
IMGT
EMBL AK080730 AK138991 AK142515 AL663082 BC086682 BC117721
GenPept AAH86682 AAI17722 BAC37998 BAE23849 BAE25095 CAI25189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca