InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnpy2

Summary

InnateDB Protein

IDBP-197238.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnpy2

Protein Name

canopy 2 homolog (zebrafish)

Synonyms

5330432A10Rik; AW229003; D10Bwg1546e; Tmem4; Zsig9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026446

InnateDB Gene

IDBG-197236 (Cnpy2)

Protein Structure

UniProt Annotation

Function

Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum {ECO:0000255PROSITE- ProRule:PRU10138}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0010629	negative regulation of gene expression
GO:0010988	regulation of low-density lipoprotein particle clearance
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process