InnateDB Protein
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IDBP-197246.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gbp3
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Protein Name
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guanylate binding protein 3
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Synonyms
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AW228655; Gbp4;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000029935
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InnateDB Gene
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IDBG-197244 (Gbp3)
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Protein Structure
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Function |
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation. {ECO:0000269PubMed:9659399}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:9659399}. Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Brain, lung, heart, spleen, kidney, liver and intestine. {ECO:0000269PubMed:9659399}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
0
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1926263
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InterPro |
IPR003191
Guanylate-binding protein, C-terminal
IPR015894
Guanylate-binding protein, N-terminal
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF02841
PF02263
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q61107
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PhosphoSite |
PhosphoSite-Q61107
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TrEMBL |
D3YVW6
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UniProt Splice Variant |
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Entrez Gene |
55932
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UniGene |
Mm.439718
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RefSeq |
NP_001276421
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MGI ID |
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MGI Symbol |
Gbp3
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OMIM |
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CCDS |
CCDS17879
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HPRD |
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IMGT |
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EMBL |
AC102108
BC019195
U44731
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GenPept |
AAA86645
AAH19195
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