Version 5.4
Homo sapiens Protein: CCDC85C
Summary
InnateDB Protein IDBP-19728.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCDC85C
Protein Name coiled-coil domain containing 85C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369592
InnateDB Gene IDBG-19726 (CCDC85C)
Protein Structure
UniProt Annotation
Function May play an important role in cortical development, especially in the maintenance of radial glia. {ECO:0000250}.
Subcellular Localization Cell junction, tight junction {ECO:0000250}. Note=Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain. Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0021987 cerebral cortex development
Cellular Component
GO:0005923 tight junction
GO:0043296 apical junction complex
Protein Structure and Domains
PDB ID
InterPro IPR019359 Protein of unknown function DUF2216, coiled-coil
PFAM PF10226
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NKD9
PhosphoSite PhosphoSite-A6NKD9
TrEMBL G3V5D5
UniProt Splice Variant
Entrez Gene 317762
UniGene Hs.738506
RefSeq NP_001138467
HUGO HGNC:35459
OMIM
CCDS CCDS45161
HPRD
IMGT
EMBL AL110504 AL160313
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca