Version 5.4
Mus musculus Protein: Lbh
Summary
InnateDB Protein IDBP-197338.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lbh
Protein Name limb-bud and heart
Synonyms 1810009F10Rik; 6720416L16Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000024857
InnateDB Gene IDBG-197336 (Lbh)
Protein Structure
UniProt Annotation
Function Modulates the activity of key transcription factors involved in cardiogenesis. {ECO:0000269PubMed:11336496, ECO:0000269PubMed:15958514}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11336496}. Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed at highest levels in heart, and at lower levels in brain, spleen, lung, liver and kidney. {ECO:0000269PubMed:11336496}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0010468 regulation of gene expression
GO:0030193 regulation of blood coagulation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1925139
InterPro IPR013294 Limb-bud-and-heart
PFAM
PRINTS PR01881
PIRSF PIRSF008130
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CX60
PhosphoSite PhosphoSite-Q9CX60
TrEMBL
UniProt Splice Variant
Entrez Gene 77889
UniGene Mm.154109
RefSeq NP_084275
MGI ID
MGI Symbol Lbh
OMIM
CCDS CCDS28964
HPRD
IMGT
EMBL AF317517 AK020110 BC026827 BC052470
GenPept AAH26827 AAH52470 AAK38204 BAB31998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca