Mus musculus Protein: Adam1a
Summary
InnateDB Protein IDBP-197350.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adam1a
Protein Name a disintegrin and metallopeptidase domain 1a
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000098320
InnateDB Gene IDBG-197348 (Adam1a)
Protein Structure
UniProt Annotation
Function May be involved in sperm-egg fusion. {ECO:0000269PubMed:8146185}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Testis. {ECO:0000269PubMed:12095680}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007339 binding of sperm to zona pellucida
GO:0007342 fusion of sperm to egg plasma membrane
Cellular Component
GO:0016021 integral component of membrane
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID MGI:2429504
InterPro IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
PFAM PF00008
PF01421
PF00200
PF01562
PF08516
PRINTS PR00289
PIRSF
SMART SM00181
SM00050
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60813
PhosphoSite PhosphoSite-Q60813
TrEMBL Q3V0H1
UniProt Splice Variant
Entrez Gene 280668
UniGene Mm.467972
RefSeq NP_742124
MGI ID
MGI Symbol Adam1a
OMIM
CCDS CCDS19637
HPRD
IMGT
EMBL AB048844 AK132804 AK133150 BC052093 U06144 U22056
GenPept AAA18423 AAA74920 AAH52093 BAB86768 BAE21366 BAE21533