Version 5.4
Homo sapiens Protein: EXOC1
Summary
InnateDB Protein IDBP-19757.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOC1
Protein Name exocyst complex component 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000326514
InnateDB Gene IDBG-19751 (EXOC1)
Protein Structure
UniProt Annotation
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 40 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0015031 protein transport
GO:0044267 cellular protein metabolic process
GO:0061024 membrane organization
Cellular Component
GO:0000145 exocyst
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR019160 Exocyst complex, component 1/SEC3
PFAM PF09763
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NV70
PhosphoSite PhosphoSite-Q9NV70
TrEMBL A0A024RDA9
UniProt Splice Variant
Entrez Gene 55763
UniGene Hs.269665
RefSeq NP_060731
HUGO HGNC:30380
OMIM 607879
CCDS CCDS3502
HPRD 07615
IMGT
EMBL AF208854 AK001755 AK027413 BC020650 BC094751 CH471057
GenPept AAF64268 AAH20650 AAH94751 BAA91886 BAB55095 EAX05474 EAX05475

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca